Impact of chemotherapy alone, and chemotherapy plus ipilimumab, on circulating immune cells in patients with metastatic bladder cancer
نویسندگان
چکیده
Impact of chemotherapy alone, and chemotherapy plus ipilimumab, on circulating immune cells in patients with metastatic bladder cancer Matthew D Galsky, Hahn Noah, Alexander Starodub, Ralph J Hauke, Przemyslaw Twardowski, Mark Fleming, Jingjing Qi, Guru Sonpavde, Manishkumar Patel, Jun Zhu, Uma Chippada-Venkata, Costantine Albany, Li Wang, Miriam Merad, William Oh, Nina Bhardwaj, Sacha Gnjatic, Seunghee Kim-Schulze
منابع مشابه
“How should we treat older patients with Metastatic Colorectal Cancer, A Review”
Nearly 50 % of newly diagnosed colorectal cancer, affect people over 70 years of age. Inclusion of older patients in clinical trials has been extremely rare. As a result, there is debate on how to manage these patients because it is still unclear how to balance the therapeutic advantages and toxicities. For patients who do not have comorbid conditions, with performance status (P.S.) 0–1, treatm...
متن کاملNeoadjuvant chemotherapy in high-risk localized prostate cancer: a systematic review
Background: The rate of recurrence and mortality in high-risk prostate cancer remains high. On the other hand, the use of chemotherapy in metastatic prostate cancer has improved overall survival of patients. The aim of this study was to evaluate the effect of neoadjuvant chemotherapy alone on increasing survival of patients with high risk localized prostate cancer Methods: This is a systematic...
متن کاملRADIOTHERAPY IN IMMUNOPROLIFERATIVE SMALL INTESTINAL DISEA SE: A RETROSPECTIVE COMPA RISON OF CHEMOTHERAPY PLUS RADIATION WITH CHEMOTHERAPY ALONE
In order to evaluate the results of abdominal radiation plus chemotherapy in cases with stage II and III of immunoproliferative small intestinal disease in comparison to chemotherapy alone, fifty-one patients referred to Shiraz University of Medical Sciences' affiliated hospitals were studied between 1980 and 1994. Out of them 38 patients who had an abdominal mass were gathered into two gro...
متن کاملCheckpoint Inhibitors for Advanced Bladder Cancer
Metastatic urothelial cancer (UC) recurring after cisplatin based combination chemotherapy represents an incurable condition for which treatment with second line chemotherapy is almost always unsuccessful in achieving prolonged remissions. The recent introduction into the therapeutic armamentarium of immune checkpoint inhibitors can potentially be a “game changer”, although success currently re...
متن کاملMathematical Modeling of Cancer Cells and Chemotherapy Protocol Dealing Optimization Using Fuzzy Differential Equations And Lypunov Stability Criterion
Mathematical models can simulate the growth and proliferation of cells in the interaction with healthy cells, the immune system and measure the toxicity of drug and its effects on healthy tissue pay. One of the main goals of modeling the structure and growth of cancer cells is to find a control model suitable for administration among patients. In this study, a new mathematical model is designed...
متن کامل